Annual report pursuant to Section 13 and 15(d)

Schedule of Recognized Stock-Based Compensation (Details)

v3.22.0.1
Schedule of Recognized Stock-Based Compensation (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation expense $ 4,292,355 $ 4,564,787
Research and Development Expense [Member]    
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation expense 1,870,000 1,897,000
General and Administrative Expense [Member]    
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation expense $ 2,422,000 $ 2,668,000